Proceedings of the National Academy of Sciences, Volume 123, Issue 31, August 2026. SignificanceThis study elucidates a vitamin D receptor–spleen tyrosine kinase–pyruvate kinase M2 (VDR–SYK–PKM2) axis through which…
Proceedings of the National Academy of Sciences, Volume 123, Issue 31, August 2026. SignificanceProteolytic activation of transcription factors has proven to serve biologically important regulatory roles. For example…
Proceedings of the National Academy of Sciences, Volume 123, Issue 31, August 2026. SignificancePandemic preparedness requires strategic stockpiling of antiviral drugs but existing stockpile estimates are based on…
Proceedings of the National Academy of Sciences, Volume 123, Issue 31, August 2026. SignificanceHermaphroditic plants commonly evolve mechanisms to resolve conflict between male and female components of fitness, for…
Proceedings of the National Academy of Sciences, Volume 123, Issue 31, August 2026. SignificanceThe global spread multidrug-resistantNeisseriagonorrhoeaethreatens to undermine antibiotic treatment. Treatment failures of…
Proceedings of the National Academy of Sciences, Volume 123, Issue 31, August 2026. SignificanceUnderstanding how social systems evolved requires knowing the ancestral social organization. Here, we tested the assumption…
Reimagining Human Movement: The Impact of Extended Reality on Physical and Emotional Experience Behind each article we publish stands a team of superheroes: authors, editors, and reviewers who chose to uphold quality…
A laboratory study reveals how underlying relationship doubts and mutual support systems influence the emotional tone and conversational engagement of romantic couples during everyday logistics and problem-solving tasks.
Psychometric evaluations of the Short Dark Tetrad (SD4; [33]) have been conducted predominantly in Western samples, and the limited evidence from non-WEIRD contexts has yielded inconsistent findings regarding its factor…
Artificial intelligence (AI) is increasingly reshaping second language (L2) learning by providing learners with more interactive, flexible, and personalized forms of support. Yet how learners’ perceptions of AI…
This study examines how exposure to artificial intelligence (AI) shapes Chinese workers’ occupational mobility and how the consequences differ across AI’s labor-saving and labor-augmenting channels. Using 2,446…
IntroductionOlder adults typically show a disproportionate decline in associative, relative to item, memory. Here, we investigated the role of stimulus presentation in a foreign language, as well as the impact of a…
IntroductionCollege students face prominent emotional and interpersonal challenges under current social and academic pressures, and social-emotional competence is essential for their mental health and healthy…
In the dynamic landscape of higher education, Physical Education (PE) teachers face unique pressures that require adaptability and innovation to effectively engage adult learners. Drawing on the Conservation of Resources…
BackgroundFacing rising global surgical volumes and healthcare workforce shortages, task shifting in anesthesia care has been widely implemented, including in China where a specialized anesthesia nursing workforce has…
IntroductionPhysical activity is an effective adjunctive therapy in schizophrenia, improving psychiatric symptoms and reducing the mortality rate. However, individuals with schizophrenia engage in lower levels of…
This study aimed to examine the multidimensional nature of Generative Artificial Intelligence (GAI) addiction among undergraduate students. For this purpose, firstly, the Generative Artificial Intelligence Addiction…
James Gibson introduced the concept of ecological physics. Gibson asserted that contemporary physics, such as general relativity, was not relevant to perceiving and acting. One area in which Gibson claimed that…
Research on well-being has predominantly relied on cross-sectional retrospective person-level assessments, which may overlook short-term fluctuations across contexts and time. The present study evaluated a daily diary…
ObjectiveThis study analyzes differences in depression-related expressions between healthcare professionals and non-healthcare individuals on Chinese social media.BackgroundSentiment plays a critical role in depression…
BackgroundAcademic life satisfaction is an important indicator of students' experiences in higher education, yet the mechanisms linking sport-related attitudes to academic life remain unclear. Guided by…
This paper examines the issue of adolescent cyber victimization through the complementary lenses of routine activity theory (RAT) and rational choice theory (RCT), which together form an integrated framework. RAT posits…
IntroductionHybrid work is increasingly widespread; however, it remains unclear whether employees benefit from these arrangements or struggle to manage work–life boundaries and achieve recovery. Focusing on two early…
Urban traffic-related air pollution and noise not only exert direct adverse effects on human health but also influence how individuals perceive and respond to these environmental stressors. The low-intervention…
This study investigated the dynamic temporal relationships among anxiety, psychological resilience, and academic engagement among junior secondary school students, with particular attention to the longitudinal mediating…
IntroductionThe formation of farmers’ well-being is closely related to digital literacy, psychological empowerment, and agricultural planting decision-making behavior. In order to explore the underlying sequential…
IntroductionAchievement emotions have received growing attention in second language research, yet little is known about how multiple emotions are subjectively organized in professionally oriented translation learning…
IntroductionVirtual influencers are increasingly deployed to mobilize prosocial causes, yet the mechanisms converting humanlike design into action remain under-specified. This study integrates social cognitive theory…
PurposeIn the context of digital transformation and intensified global competition, career sustainability has become a core issue for both organizational and individual development. This study investigates how employee…
As a critical factor in early childhood development (ECD), parenting stress has been demonstrated to adversely affect maternal well-being and child developmental outcomes. This study examined the association between…