Complete deletion of the DMD gene provides insights into the function of dystrophin
Proceedings of the National Academy of Sciences, Volume 123, Issue 33, August 2026.
Current reporting, research and professional developments across Research, curated for psychologists and behavioral-health professionals.
Proceedings of the National Academy of Sciences, Volume 123, Issue 33, August 2026.
Proceedings of the National Academy of Sciences, Volume 123, Issue 33, August 2026.
Proceedings of the National Academy of Sciences, Volume 123, Issue 33, August 2026.
Proceedings of the National Academy of Sciences, Volume 123, Issue 33, August 2026.
Proceedings of the National Academy of Sciences, Volume 123, Issue 33, August 2026. Redistributive policies designed to reduce economic inequality through taxes and transfers (e.g., safety-net benefits funded by…
Proceedings of the National Academy of Sciences, Volume 123, Issue 33, August 2026. Small interfering RNAs (siRNAs) are widely used to repress gene expression. For human Argonaute2 (AGO2) to cleave target RNA, siRNAs…
Proceedings of the National Academy of Sciences, Volume 123, Issue 33, August 2026.
Proceedings of the National Academy of Sciences, Volume 123, Issue 33, August 2026. SignificanceOn orbital timescales, terrestrial rainfall and Arabian Sea upwelling records of South Asian summer monsoon (SASM) evolve…
Proceedings of the National Academy of Sciences, Volume 123, Issue 33, August 2026. SignificanceExon-skipping antisense oligonucleotides (ASOs) have been approved for the treatment of Duchenne muscular dystrophy (DMD)…
Proceedings of the National Academy of Sciences, Volume 123, Issue 33, August 2026. SignificanceThe adult mammalian brain cannot efficiently replace neurons lost after injury or due to neurodegenerative disease…
Proceedings of the National Academy of Sciences, Volume 123, Issue 33, August 2026. SignificanceParkinson’s disease is caused in part by the toxic accumulation of α-synuclein, which damages brain cells that produce…
Proceedings of the National Academy of Sciences, Volume 123, Issue 33, August 2026. SignificanceInvasive infections with the fungusCandida albicansthreaten progress in oncology, transplantation, surgery, and many other…
Proceedings of the National Academy of Sciences, Volume 123, Issue 33, August 2026. SignificanceLipid droplets (LDs) have long been viewed merely as lipid storage units, but their role in plant immunity remains poorly…
Proceedings of the National Academy of Sciences, Volume 123, Issue 33, August 2026. SignificanceViruses with large DNA genomes often encode metabolic enzymes that reshape host physiology, yet their ability to control…
Proceedings of the National Academy of Sciences, Volume 123, Issue 33, August 2026. SignificanceThe lack of a cell wall affords animal cells diverse functionality but renders them vulnerable to plasma membrane (PM)…
Proceedings of the National Academy of Sciences, Volume 123, Issue 33, August 2026. SignificanceReceptor tyrosine kinase (RTK) fusions are chimeric oncoproteins that combine the intracellular domain of an RTK with an…
Proceedings of the National Academy of Sciences, Volume 123, Issue 33, August 2026. SignificanceBacterial reaction centers are transmembrane protein–cofactor complexes that are central to an ancient and preserved…
Proceedings of the National Academy of Sciences, Volume 123, Issue 33, August 2026. SignificanceWe use more than 900 million linked employer–employee records covering the entire formal workforce of Brazil to examine when…
Proceedings of the National Academy of Sciences, Volume 123, Issue 33, August 2026. SignificanceThis work introduces molecular assembly (MA) as a universal, quantitative biosignature that measures how difficult it is to…
Proceedings of the National Academy of Sciences, Volume 123, Issue 33, August 2026. SignificanceAlthough immune checkpoint inhibitors (ICIs) have revolutionized the clinical management of non–small cell lung cancers…
Proceedings of the National Academy of Sciences, Volume 123, Issue 33, August 2026. SignificanceUnderstanding light propagation and energy deposition in biological tissues is essential for advancing photodynamic and…
Proceedings of the National Academy of Sciences, Volume 123, Issue 33, August 2026. SignificanceLymphocytes, including T, B, and NK cells, achieve functional maturation through a process known as education, which ensures…
Proceedings of the National Academy of Sciences, Volume 123, Issue 33, August 2026. SignificanceAnimal groups detect predators using either a many-eyes strategy (all members maintain a low-level vigilance) or a sentinel…
Proceedings of the National Academy of Sciences, Volume 123, Issue 33, August 2026. SignificanceIllegal drug markets generate enormous harms and involve large amounts of money. This article provides a primer on illegal…
Proceedings of the National Academy of Sciences, Volume 123, Issue 33, August 2026. SignificanceBlack–White mortality disparities remain a persistent form of inequality in the United States. This study provides evidence…
Proceedings of the National Academy of Sciences, Volume 123, Issue 33, August 2026. SignificanceIn modern Africa, savannas cover ~50% of the continent, provide critical ecosystem services, and affect global climate…
Proceedings of the National Academy of Sciences, Volume 123, Issue 33, August 2026. About 3.5 million fishing vessels ply the world’s oceans, providing livelihoods and food for millions of people. Sound management is key…
Proceedings of the National Academy of Sciences, Volume 123, Issue 33, August 2026. In the United States, the legal status of the 30 to 40 million annual firearms transactions is defined by state and federal regulations…
Proceedings of the National Academy of Sciences, Volume 123, Issue 33, August 2026. SignificanceDiving while supplied by compressed gas can be limited in duration by the need to perform prolonged decompression in order…
Proceedings of the National Academy of Sciences, Volume 123, Issue 33, August 2026. SignificanceIllegal markets present important challenges to society and have distinctive features, but scientific research on them has…
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