Current reporting, research and professional developments across Neuropsychology, curated for psychologists and behavioral-health professionals.
Integrating different sources of information is essential to successful spatial navigation. For instance, animals often rely on a combination of visual impressions, self-motion, olfaction, and other signals to navigate…
Neuronal senescence, triggered by oxidative stress and inflammatory responses, is a significant risk factor for brain aging, ultimately leading to cognitive decline. Apelin-13, an exercise-induced myokine, exhibits…
Accumulating evidence indicates that gut microbiota plays a role in the progression of Parkinson’s disease (PD). Microbiota-based treatments for prodromal PD, which is accompanied by a wide range of neuropsychiatric…
Traumatic brain injury (TBI) elicits robust neuroinflammation and oxidative stress, coupled with an acute inhibition of macro-autophagy (autophagy) in neurons and microglia. Rubicon (Rubcn), a Beclin1 interacting protein…
The platelet to highdensity lipoprotein cholesterol ratio (PHR) is an emerging indicator reflecting the balance between thrombogenesis and lipid metabolism inflammation. This study aimed to investigate the relationship…
Hereditary defects in the function of the inwardly rectifying potassium channel Kir7.1 in the retinal pigment epithelium are associated with the ocular diseases retinitis pigmentosa, Leber congenital amaurosis, and…
The workings of the brain are often compared to those of a computer. Some researchers are testing this analogy to its limits, attempting to build computers containing laboratory-grown cultures of brain cells. In doing…
End-stage renal disease (ESRD) patients exhibit a high prevalence of multidimensional frailty, yet its neurobiological correlates remain unclear. This study investigated neuroimaging correlates of frailty in ESRD and…
Sleep deprivation can be dangerous, but it’s difficult to measure.Credit: Getty How does the brain know when it’s time to wake up? Researchers have identified1 a chemical signal that serves as a timer in the mouse brain…
Two scientists blend their love of music and science in different ways. This is a preview of subscription content, access via your institution Access Nature and 54 other Nature Portfolio journals Get Nature+, our…
This study investigates how heterogeneity in lifestyle and physical fitness shapes patterns of brain ageing in depression. The study sample included medically healthy adults from the UK Biobank (44–82 years) with a…
Habits are essential for sustaining adaptive behaviors but can also lead to maladaptive behaviors such as compulsive and addictive disorders. They emerge through a shift in decision-making from motivation-driven strategy…
Calcium imaging is a central method in neuroscience but it records neuronal activity only indirectly and thereby produces results that are difficult to interpret. Here we evaluate the GCaMP8 calcium indicator variants…
The brainâs capacity for information processing depends on precisely regulated energy dynamics. Yet how metabolic supply adapts to shifting computational demands across brain states remains unclear. Using wide-field…
Spontaneous subarachnoid hemorrhage (SAH) remains a life-threatening type of hemorrhagic stroke. Astrocytes are key cellular responders after SAH. We designed the current study to elucidate the global astrocyte reaction…
Post-mortem tau pathology is frequently observed in Parkinsonâs disease (PD) using immunohistochemistry (IHC) to measure large inclusions. However, small protein aggregates that precede inclusions are considered a…
Correction to: Molecular Psychiatry https://doi.org/10.1038/s41380-026-03560-0; published online 02 April 2026 Following publication of this article, the authors identified an error in the corresponding authorship…
Voltage-gated sodium channels regulate neuronal excitability and synaptic transmission in the postnatal and adult brain. The gene SCN2A, encoding the sodium channel Nav1.2, regulates synaptic development and variants in…
What makes some people willing to help strangers at a personal cost, while others are more hesitant or selective? Early life adversity - such as neglect or abuse - may shape how we respond to strangers in need later in…
Air pollution may pose a risk beyond the lungs, with growing research linking long-term exposure to cognitive decline and dementia. More than 57 million people worldwide live with dementia, while ...
Your brain is ageing long before you notice it. Read on to know what neurologist says about managing healthy brain functioning after you turn 30.
Participants with metabolic syndrome had a significantly higher brain age gap than those without the condition, indicating accelerated brain aging. Brain age increased progressively with the number of ...
Restricting daily eating to an 8 to 9 hour window yields cognitive improvements in spatial planning and problem-solving for older, overweight women beyond the benefits of caloric reduction alone.
Over subsequent decades, couples accumulate shared experiences. They live in the same neighbourhoods, breathe the same air, eat similar diets, remain similarly active and encounter many of the same ...
EATING all your food in an eight to nine hour window each day could reduce your risk of dementia, a study has suggested. What’s more, stopping eating four hours before going to sleep may ...
Scientists have identified a possible tipping point that helps determine whether Alzheimer’s-related brain changes lead to dementia. The key may lie in how the brain’s immune cells respond to plaques and tau, offering a…
Julianne Moore's crucial health message! Why the Oscar winner wants you to prioritize brain health before Alzheimer's symptoms start ...
A recent study has discovered that the changes human brain undergoes in 40s and 50s could influence the risk for developing dementia in the future.
A landmark study says your brain can get sharper, not duller, with age. But is it as easy as it sounds?
Alzheimer’s disease is the most common cause of dementia and affects millions of people around the world. It slowly damages memory, thinking and the ability to perform everyday tasks. Although ...
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